Difference Between Suboxone Strips and Suboxone Pills

Discover the difference between Suboxone strips and pills, their effects, costs, and user experiences.

Sep 05, 2024 by Arista Recovery Staff

Understanding Suboxone Forms

As part of the comprehensive approach to treating opioid use disorder, it's important to understand the different forms of medication available. Suboxone, a medication used in the treatment of opioid addiction, is available in different forms, each with its own unique features and advantages. In this section, we will delve into the difference between Suboxone strips and Suboxone pills.

Suboxone Strips vs. Suboxone Pills

Suboxone is available in a variety of dosage forms, including buccal film, sublingual film, and sublingual tablet. However, the two most common forms are Suboxone strips and Suboxone pills.

Suboxone strips, also known as sublingual films, are thin, dissolvable films that are placed under the tongue to dissolve. These strips are absorbed faster and more effectively than pills, delivering a controlled dose of medication directly into the bloodstream. This form of Suboxone dissolves much quicker than tablets, making them associated with lower abuse rates as they can't be crushed and inhaled.

On the other hand, Suboxone pills are taken orally and swallowed. This form of the medication releases gradually into the body over time, providing a sustained release of the medication.

It's important to note that Suboxone strips have a slightly higher bioavailability than tablets, which means that a higher amount of the medication is available for the body to use. This may require a subtle dose adjustment if switching between the two forms. However, both forms are effective in helping individuals deal with opioid use disorder.

In summary, the primary difference between the two forms lies in their method of administration and absorption, with strips being absorbed directly into the bloodstream and pills being swallowed and absorbed gradually. The choice between the two will largely depend on individual preference and the specific needs of the patient.

Composition and Dosage Forms

Understanding the composition and different dosages of Suboxone is key to grasping the difference between Suboxone strips and Suboxone pills, and how these forms can affect individuals who use Fentanyl.

Buprenorphine and Naloxone Combination

Suboxone is a medication that contains a combination of buprenorphine and naloxone. Buprenorphine is an opioid medication, while naloxone blocks the effects of opioids, preventing potential abuse of the medication. This unique combination makes Suboxone a vital tool in the management of opioid dependence.

Specifically, Suboxone contains buprenorphine and naloxone in a 4:1 ratio. Buprenorphine acts as the active ingredient, while naloxone remains inactive unless the medication is misused intravenously or endoscopically. In such cases, naloxone effectively blocks the opioid receptors and can reverse the effects of other opioids [5].

Different Dosage Forms Available

Suboxone is available in different dosage forms, which include buccal film, sublingual film, and sublingual tablet.

Suboxone strips are designed to be placed under the tongue or inside the cheek where they are absorbed directly into the bloodstream. These strips can take up to 6.6 minutes to dissolve completely.

On the other hand, Suboxone tablets are also placed sublingually (under the tongue) and can take up to 12.4 minutes to dissolve. The longer dissolution time may affect the absorption rate and effectiveness of the medication [3].

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Dosage FormDissolution Time
Suboxone StripsUp to 6.6 minutes
Suboxone TabletsUp to 12.4 minutes

The choice between Suboxone strips and tablets can depend on a variety of factors, including patient preference, convenience, and the specific needs of the individual's treatment plan. An understanding of these differences can help inform decisions about the most suitable form of Suboxone for each unique situation.

Administration and Usage

When discussing the difference between Suboxone strips and Suboxone pills, one of the primary distinctions lies in the method of administration. Both forms contain the same active ingredients, buprenorphine and naloxone, but they are administered in unique ways.

Method of Administration

Suboxone strips, also referred to as sublingual films, are placed under the tongue or inside the cheek until they dissolve. This method allows the medication to be absorbed directly into the bloodstream through the oral mucosa, providing quick onset of effects. Suboxone strips are designed to dissolve completely in approximately 6.6 minutes.

On the other hand, Suboxone pills, or sublingual tablets, are taken orally. They are placed under the tongue until they dissolve, which can take up to 12.4 minutes. This method also allows the medication to be absorbed directly into the bloodstream, ensuring quick onset of effects [1].

It's important to note that the method of administration can influence the onset and duration of effects. Therefore, users should follow the instructions provided by their healthcare provider to ensure optimal results.

Indications and Usage

Both Suboxone strips and pills are indicated for use in people who are dependent on opioids. They are used as part of a comprehensive treatment program that includes counseling and psychosocial support. The goal of Suboxone treatment is to help the individual stop using opioids by managing withdrawal symptoms and reducing cravings.

Suboxone works by binding to the same receptors in the brain as opioids, but in a way that helps to suppress withdrawal symptoms and reduce cravings. Because Suboxone also contains naloxone, an opioid antagonist, it discourages misuse and helps prevent dependency and addiction.

While Suboxone can be picked up in pharmacies, methadone, another medication used in the treatment of opioid use disorder, must be taken in person at opioid treatment programs.

It's important for individuals using Suboxone, whether in strip or pill form, to do so under the supervision of a healthcare provider. This ensures safe use and allows for adjustments to the treatment plan as necessary.

Effectiveness and Side Effects

Understanding the effectiveness and potential side effects of both Suboxone strips and pills is crucial for individuals seeking treatment for opioid use disorder. This section will delve into the efficacy of these medications in treating opioid dependency and discuss the possible risks and side effects associated with their use.

Efficacy in Treating Opioid Use Disorder

Suboxone, whether in the form of strips or pills, is often employed in the treatment of opioid dependence. Its effectiveness lies in its ability to alleviate withdrawal symptoms, reduce cravings, and prevent opioid overdose and deaths [4].

Both Suboxone strips and pills have been proven effective in treating opioid cravings, withdrawal symptoms, and preventing relapse. Numerous studies have demonstrated their ability to support successful outcomes in addiction recovery [4].

FormEffectiveness
Suboxone StripsAlleviates withdrawal symptoms, reduces cravings, prevents opioid overdose
Suboxone PillsAlleviates withdrawal symptoms, reduces cravings, prevents opioid overdose

It's important to consult with a healthcare professional before starting Suboxone treatment to determine its suitability for individual situations.

Potential Side Effects and Risks

Despite its efficacy, Suboxone can cause serious side effects such as breathing problems, liver issues, serotonin syndrome, and opioid withdrawal symptoms if misused or taken improperly [1]. These risks underscore the importance of using the medication as directed under the supervision of a healthcare provider.

Side EffectsSuboxone StripsSuboxone Pills
Breathing ProblemsYesYes
Liver IssuesYesYes
Serotonin SyndromeYesYes
Opioid Withdrawal SymptomsYesYes

It is critical to be aware of these potential risks when considering the use of Suboxone strips or pills for opioid use disorder. Always consult a healthcare provider for personalized advice and guidance.

Cost and Availability

When considering the choice between Suboxone strips and Suboxone pills, the cost and availability of these two forms of Suboxone might significantly impact your decision.

Price Comparison: Strips vs. Pills

When it comes to cost, Suboxone pills are typically more cost-effective than strips. For instance, a range of 14 tablets of 2 mg Buprenorphine (Suboxone) pills generally costs between $25 and $45. On the other hand, strips of the same dosage and count can cost anywhere from $40 to $80.

FormDosage (mg)CountPrice Range ($)
Suboxone Pills21425 - 45
Suboxone Strips21440 - 80

The above table clearly illustrates the difference in price between Suboxone strips and Suboxone pills for the same dosage and count.

However, it's important to note that prices may vary depending on the location and pharmacy.

Insurance Coverage and Access

Insurance coverage can play a significant role in the cost of Suboxone, with some insurance plans covering either form of this medication. It's advisable to check with your insurance provider to understand what is covered under your plan.

In terms of access, both Suboxone strips and pills are widely available at pharmacies. However, some patients might have a preference for one form over the other. For instance, Suboxone pills may be more favorable in taste compared to the strips, with anecdotal reports suggesting that some individuals find the pills more palatable, while the strips may leave a stronger and more disagreeable aftertaste in the mouth.

In summary, while the cost factor can sway one's choice towards Suboxone pills, factors such as taste and ease of administration might make Suboxone strips a more preferable choice for some individuals. It's important to discuss these factors with your healthcare provider to make an informed decision.

Comparison Studies and User Experiences

In order to understand the difference between Suboxone strips and Suboxone pills, it can be helpful to look at research findings and user experiences. These sources of information can provide insight into how each form of Suboxone is absorbed and its effectiveness, as well as preferences among users.

Research Findings on Absorption and Effectiveness

Studies have shown some differences in the way Suboxone strips and pills are absorbed by the body. Suboxone strips dissolve much quicker than tablets, therefore they tend to absorb faster and more effectively, allowing individuals to feel the effects of the medication sooner Northstar Behavioral Health. The quicker dissolution and absorption can be beneficial in managing withdrawal symptoms and craving control.

In addition to quicker absorption, Suboxone strips have a slightly higher bioavailability than tablets. This may require a subtle dose adjustment if switching between the two forms, but both are effective in helping individuals deal with opioid use disorder.

Studies have also suggested that the films are associated with lower abuse rates than tablets, making them harder to abuse as they can't be crushed and inhaled. A study published in 2023 found that Suboxone films were associated with lower abuse rates than tablets, suggesting that doctors should choose films in settings where the potential for substance abuse is high Boca Recovery Center. Another study comparing abuse rates between sublingual BUP-NAL films and tablets found that tablets had a higher prevalence of abuse by any route of administration compared to films, even after adjusting for prescription volume NCBI Bookshelf.

User Preferences and Experiences

User experiences with Suboxone strips and pills can vary. Some individuals may prefer the convenience and quicker absorption of the strips, while others might prefer the familiarity of pills. However, according to research, the quick dissolution and absorption of Suboxone strips make them a popular choice among users, as they allow individuals to feel the effects of the medication faster. Furthermore, the lower potential for abuse associated with the strips may make them a more suitable choice in certain settings.

In conclusion, both Suboxone strips and pills can be effective in treating opioid use disorder, but they offer different benefits and potential risks. The choice between the two will depend on the specific needs and preferences of the individual, as well as the recommendation of their healthcare provider.

Differentiating Suboxone from Methadone

While both Suboxone and Methadone are used in managing opioid dependency, there are stark differences in their mechanisms of action and safety profiles.

Mechanism of Action Comparison

The primary difference between methadone and Suboxone lies in how they stimulate the mu opioid receptor. Buprenorphine in Suboxone is a partial agonist of the mu receptor, partially occupying it. In contrast, methadone is a full agonist, fully occupying the mu-opioid receptor.

Additionally, Suboxone contains buprenorphine and naloxone in a 4:1 ratio. Buprenorphine is the active ingredient, while naloxone is inactive unless the medication is misused intravenously or endoscopically. Naloxone blocks the opioid receptors and can reverse the effects of other opioids [5].

OpioidAgonist TypeOpioid Receptor OccupancyContains Naloxone
SuboxonePartialPartialYes
MethadoneFullFullNo

Safety Profile and Risks Comparisons

In terms of safety, Suboxone significantly reduces the risk of respiratory depression or sedation due to the limit on the activation level of the opioid receptors in the brain by the buprenorphine, which is a partial agonist. This sets it apart from full agonists like heroin, oxycodone, fentanyl, and methadone, which have greater side effects.

Moreover, buprenorphine, the active ingredient in Suboxone, is a partial agonist with a 'ceiling effect.' This means its effects plateau after a certain dosage. It must be ingested sublingually to increase its capacity, as its bioavailability is low if swallowed. Naloxone becomes active if buprenorphine is misused by injection [5].

OpioidRespiratory Depression RiskMisuse Risk
SuboxoneLow (due to partial agonist)Lowered by presence of naloxone
MethadoneHigher (due to full agonist)Higher (lacks naloxone)

It's important that individuals seeking treatment for opioid use disorder discuss these differences with their healthcare provider to determine the best treatment option for their individual needs.

References

[1]: https://www.drugs.com/suboxone.html

[2]: https://americanaddictioncenters.org/suboxone/side-effects

[3]: https://bocarecoverycenter.com/medication-assisted-mat/suboxone/pills-vs-strips/

[4]: https://www.newhorizonscenterspa.org/blog/difference-between-suboxone-strips-and-suboxone-pills

[5]: https://www.confidanthealth.com/buprenorphine-suboxone-and-subutex/suboxone-ingredients

[6]: https://www.northstarbehavioralhealthmn.com/resources/difference-between-suboxone-strips-and-suboxone-pills

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